Antigeenpresentatie  bij SARS-CoV-2-infectie

Antigeenpresentatie  bij SARS-CoV-2-infectie: de rol van klasse I HLA- en ERAP-polymorfismen

Gezien de zeer polymorfe aard van humaan leukocytenantigeen (HLA)-moleculen, is het niet verwonderlijk dat ze fungeren als belangrijke regulatoren van de immuunrespons van de gastheer op bijna alle binnendringende pathogenen, waaronder SARS-CoV-2 , het etiologische agens dat verantwoordelijk is voor de recente COVID-19 -19 pandemie. Er zijn al verschillende correlaties vastgesteld tussen de expressie van een specifiek HLA-allel/haplotype en gevoeligheid/progressie van SARS-CoV-2-infectie en er komen voortdurend nieuwe bij. Beschermende en schadelijke HLA-varianten zijn beschreven in zowel milde als ernstige vormen van de ziekte, maar gezien de enorme hoeveelheid bestaande varianten zijn de gegevens die in zo’n korte tijdspanne zijn verzameld tot op zekere hoogte verwarrend en tegenstrijdig.

Het doel van deze mini-review is om een ​​momentopname te geven van de belangrijkste bevindingen die tot nu toe zijn verzameld over de HLA-SARS-CoV-2-interactie, om dit ingewikkelde garen gedeeltelijk te ontwarren. Als sleutelfactoren bij het genereren van antigene peptiden die door HLA-moleculen moeten worden gepresenteerd , zal ook de rol van ERAP1 en ERAP2 bij SARS-CoV-2-infectie worden herzien.

Beoordeling van immunogeniciteit en veiligheid in twee productiepartijen van een 3- antigeen  hepatitis B-vaccin, Sci-B-Vac®, vergeleken met Engerix-B® bij gezonde Aziatische volwassenen: een gerandomiseerde klinische fase 3-studie

Achtergrond:  Sci-B-Vac®, een 3-antigeen hepatitis B-vaccin (3A-HBV), bevat alle drie de envelopeiwitten van het recombinante hepatitis B-virus (HBV) (S, pre-S1 en pre-S2). In 2005 verplaatste de productie van 3A-HBV de faciliteiten (A naar B), waar het nog steeds wordt geproduceerd.

Methoden:  Deze fase 3, enkelblinde, gerandomiseerde studie, uitgevoerd op één locatie in Vietnam, vergeleek de werkzaamheid en veiligheid tussen twee 3A-HBV-partijen, partij A en partij B, en een enkel antigeen hepatitis B-vaccin (1A-HBV) , Engerix-B®. Het primaire doel was om op dag 210 gelijkwaardigheid aan te tonen van twee 3A-HBV-lots in seroprotectiepercentage (SPR; gedefinieerd als proportion deelnemers dat hepatitis B-oppervlakteantigeenantilichaam [anti-HBs]-titers ≥ 10 mIU/ml bereikte). Secundaire doelstellingen waren het beoordelen van de immunogeniciteit op dag 180, 210 en 360, en de veiligheid van 3A-HBV.

Resultaten:  3A-HBV SPR-equivalentie werd aangetoond op dag 210 (partij A: 97,3% [95% BI: 92,4%, 99,4%] vs. partij B: 100,0% [97,0%, 100,0%]). Vergeleken met 1A-HBV was de SPR van partij B hoger op dag 180 (98,3% vs. 81,2%; verschil: 17,1% [9,7%, 24,6%]) en niet-inferieur op dag 210 (100% vs. 98,3%; verschil : 1,7% [-0,6%, 4,1%]). 3A-HBV partij B vertoonde dezelfde SPR na 2 doses (98,3%) als 1A-HBV na Three doses (98,3%). Bijwerkingen (AE’s) waren vergelijkbaar met beide 3A-HBV-partijen (partij A: 68,7% vs. partij B: 54,2%), maar hoger dan 1A-HBV (35,3%). Vaccinatiegerelateerde bijwerkingen omvatten voorbijgaande pijn op de injectieplaats (38,9%), myalgie (9,3%) en vermoeidheid (7,5%). Er werden acht ernstige bijwerkingen gemeld (partij A: 3/134 [2,2%]; partij B: 1/134 [0,8%]; 1A-HBV: 4/133 [2,3%]). Eén ernstige AE, syncope, werd opgemerkt als waarschijnlijk gerelateerd aan onderzoeksvaccin, lot B.

Conclusies:  De twee 3A-HBV-partijen hadden een gelijkwaardige immunogeniciteit, maar partij B veroorzaakte een snellere aanvang van seroprotectie en hogere anti-HBs-titers dan zowel partij A als 1A-HBV in een Aziatische populatie. Dit ondersteunt 3A-HBV lot B als een effectieve keuze voor HBV-vaccinatie, met een gunstig veiligheidsprofiel.

robegids
robegids

Influenza A Virus Antigen (H5N1)

VAng-Lsx011-1mL 1 mL
EUR 883.2
Description: Natural antigen of Influenza A virus subtype H5N1.

Influenza A (H1N1) Antigen Liquid

IFLUAH1N1ALR1ML each
EUR 771
Description: Influenza A (H1N1) Antigen Liquid

Influenza A (H3N2) Antigen Liquid

IFLUAH3N2ALR1ML each
EUR 754
Description: Influenza A (H3N2) Antigen Liquid

Influenza A (H3N2) Antigen Protein

abx061421-1ml 1 ml
EUR 718.8

Influenza B Antigen

abx670262-1ml 1 ml
EUR 510

Influenza A Strain A/Kiev/301/94 (H3N2) Antigen

11-568 0.1 mg
EUR 632.4
Description: Influenza A (A/Kiev/301/94) (H3N2), Influenza Virus Type A (H3N2), Strain A/Kiev/301/94

Influenza A Strain A/Panama/2007/99 (H3N2) Antigen

11-570 0.05 mg
EUR 632.4
Description: Influenza A (A/Panama/2007/99) (H3N2), Influenza Virus Type A (H3N2), Strain A/Panama/2007/99

Influenza A Strain A/Beijing/262/95 (H1N1) Antigen

11-566 0.1 mg
EUR 632.4
Description: Influenza A (A/Beijing/262/95), Influenza Virus, Type A (H1N1), Strain A/Beijing/262/95

Recombinant Avian influenza Antigen

E41H050 100ug
EUR 395

Influenza A Strain A/Brisbane/10/07 (H3N2) Antigen

11-567 0.1 mg
EUR 632.4
Description: Influenza A (A/Brisbane/10/07), Influenza A Virus, Strain A/Brisbane/10/07 (H3N2)

Influenza A Strain A/Shangdong/9/93 (H3N2) Antigen

11-571 0.1 mg
EUR 632.4
Description: Influenza A (A/Shangdong/9/93) (H3N2), Influenza Virus, Type A, Strain A/Shangdong/9/93, (H3N2)

Influenza A Strain A/Wisconsin/67/05 (H3N2) Antigen

11-573 0.1 mg
EUR 632.4
Description: Influenza A (A/Wisconsin), Influenza A Virus, Strain A/Wisconsin/67/05 (H3N2)

Influenza A Strain A/Kiev/301/94 (H3N2) Antigen Liquid

IFLUAKV30194H3N2ALR100UG each
EUR 738
Description: Influenza A Strain A/Kiev/301/94 (H3N2) Antigen Liquid

Recombinant Avian influenza H5 Antigen

E41H045 100ug
EUR 395

Recombinant Avian influenza H9 Antigen

E41H046 100ug
EUR 395

Influenza A Strain A/Panama/2007/99 (H3N2) Antigen Liquid

IFLUAPNA200799H3N2ALR50UG each
EUR 738
Description: Influenza A Strain A/Panama/2007/99 (H3N2) Antigen Liquid

Influenza A Strain A/Beijing/262/95 (H1N1) Antigen Liquid

IFLUABJ26295H1N1ALR100UG each
EUR 738
Description: Influenza A Strain A/Beijing/262/95 (H1N1) Antigen Liquid

Influenza A Strain A/Solomon Islands/03/06 (H1N1) Antigen

11-572 0.1 mg
EUR 632.4
Description: Influenza A (A/Solomon Island), Influenza A Strain A/Solomon Islands/03/06 (H1N1)

Influenza A Strain A/Brisbane/10/07 (H3N2) Antigen Liquid

IFLUABN1007H3N2ALR100UG each
EUR 738
Description: Influenza A Strain A/Brisbane/10/07 (H3N2) Antigen Liquid

Influenza A antibody

10-1096 500 ug
EUR 249.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-1097 1 mg
EUR 418.8
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-1098 1 mg
EUR 726
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-1099 1 mg
EUR 726
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-1100 500 ug
EUR 418.8
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-1101 1 mg
EUR 726
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-1102 500 ug
EUR 418.8
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-1103 500 ug
EUR 418.8
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-1241 500 ug
EUR 418.8
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-1243 500 ug
EUR 418.8
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-7866 1 mg
EUR 483.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-7867 1 mg
EUR 483.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50A 1 mg
EUR 603.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50B 1 mg
EUR 470.4
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50C 1 mg
EUR 470.4
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50D 1 mg
EUR 334.8
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50E 1 mg
EUR 334.8
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50F 1 mg
EUR 327.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50G 1 mg
EUR 489.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50H 1 mg
EUR 649.2
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50I 1 mg
EUR 489.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50K 1 mg
EUR 327.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50L 1 mg
EUR 360
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50M 1 mg
EUR 360
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50N 1 mg
EUR 360
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50O 1 mg
EUR 360
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50P 1 mg
EUR 360
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50Q 1 mg
EUR 327.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50R 1 mg
EUR 327.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50S 1 mg
EUR 327.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50T 1 mg
EUR 327.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10-I50U 1 mg
EUR 327.6
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10C-CR1306M1 100 ug
EUR 607.2
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10C-CR1306M2 100 ug
EUR 337.2
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10R-I131a 1 mg
EUR 571.2
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

10R-I131b 1 mg
EUR 586.8
Description: Mouse monoclonal Influenza A antibody

Influenza A antibody

70R-IR080 100 ug
EUR 418.8
Description: Affinity purified Rabbit polyclonal Influenza A antibody

Influenza A antibody

70R-IR082 100 ug
EUR 360
Description: Affinity purified Rabbit polyclonal Influenza A antibody

Influenza A Strain A/Shangdong/9/93 (H3N2) Antigen Liquid

IFLUASHDG993H3N2ALR100UG each
EUR 738
Description: Influenza A Strain A/Shangdong/9/93 (H3N2) Antigen Liquid

Influenza A Strain A/Wisconsin/67/05 (H3N2) Antigen Liquid

IFLUAWI6705H3N2ALR100UG each
EUR 738
Description: Influenza A Strain A/Wisconsin/67/05 (H3N2) Antigen Liquid

Influenza A Strain A/New Caledonia/20/99 IVR 116 (H1N1) Antigen

11-569 0.1 mg
EUR 632.4
Description: Influenza A (A/New Caledonia), Influenza Virus, Type A (H1N1), Strain A/New Caledonia/20/99 IVR116

Avian Influenza A Nucleoprotein Antigen Capture ELISA Kit

DEIA2026 2 x 96T
EUR 1554
Description: This kit is a highly sensitive and specific enzyme immunoassay for the detection of Influenza A nucleoprotein antigen in complex sample matrices derived from both human and veterinary sources.

Influenza A Strain A/Solomon Islands/03/06 (H1N1) Antigen Liquid

IFLUASOIS0306H1N1ALR100UG each
EUR 738
Description: Influenza A Strain A/Solomon Islands/03/06 (H1N1) Antigen Liquid

Influenza A NP Antibody

abx021947-1mg 1 mg
EUR 794.4

Influenza A NP Antibody

abx021948-1mg 1 mg
EUR 794.4

Influenza A NP Antibody

abx021949-1mg 1 mg
EUR 1220.4

Influenza A NP Antibody

abx021950-1mg 1 mg
EUR 1220.4

Influenza A NP Antibody

abx021951-1mg 1 mg
EUR 1220.4

Influenza A NP Antibody

abx021952-1mg 1 mg
EUR 794.4

Influenza A NP Antibody

abx021953-1mg 1 mg
EUR 794.4

Influenza A NP Antibody

abx021954-1mg 1 mg
EUR 794.4

Influenza A NP Antibody

abx021957-1mg 1 mg
EUR 1220.4

Influenza A NP Antibody

abx021958-1mg 1 mg
EUR 1220.4

Influenza A NP Antibody

abx021959-1mg 1 mg
EUR 1387.2

Influenza A H5 Antibody

abx021963-1mg 1 mg
EUR 1328.4

Influenza A H1 Antibody

abx021964-1mg 1 mg
EUR 1111.2

Influenza A H1 Antibody

abx021965-1mg 1 mg
EUR 1111.2

Influenza A H1 Antibody

abx021966-1mg 1 mg
EUR 1161.6

Influenza A H1 Antibody

abx021967-1mg 1 mg
EUR 1161.6

Influenza A H1 Antibody

abx021968-1mg 1 mg
EUR 1161.6

Influenza A H1 Antibody

abx021969-1mg 1 mg
EUR 1161.6

Influenza A H1 Antibody

abx021970-1mg 1 mg
EUR 1161.6

Influenza A H2 Antibody

abx021972-1mg 1 mg
EUR 1045.2

Influenza A H5 Antibody

abx021979-1mg 1 mg
EUR 1296

Influenza A H5 Antibody

abx021985-1mg 1 mg
EUR 1220.4

Influenza A H5 Antibody

abx021986-1mg 1 mg
EUR 1220.4

Influenza A H5 Antibody

abx021987-1mg 1 mg
EUR 1328.4

Influenza A H5 Antibody

abx021988-100ug 100 ug
EUR 1479.6

Influenza A H5 Antibody

abx021989-1mg 1 mg
EUR 1479.6

Influenza A H5 Antibody

abx021991-100ug 100 ug
EUR 594

Influenza A H7 Antibody

abx021994-1mg 1 mg
EUR 1028.4

Influenza A H7 Antibody

abx021995-1mg 1 mg
EUR 1028.4

Influenza A NP Antibody

abx022000-1mg 1 mg
EUR 828

Influenza A H1 Antibody

abx023068-100ug 100 ug
EUR 1011.6

Influenza A N1 Antibody

abx023070-100ug 100 ug
EUR 1011.6

Influenza A (NP) Antibody

abx023634-1mg 1 mg
EUR 718.8

Influenza A (NP) Antibody

abx023635-1mg 1 mg
EUR 718.8

Influenza A (NP) Antibody

abx023636-1mg 1 mg
EUR 718.8

Influenza A (NP) Antibody

abx023637-1mg 1 mg
EUR 718.8

Influenza A (NP) Antibody

abx023666-1mg 1 mg
EUR 718.8

Influenza A (NP) Antibody

abx023667-1mg 1 mg
EUR 718.8

Influenza A (NP) Antibody

abx023668-1mg 1 mg
EUR 718.8

Influenza A (NP) Antibody

abx023669-1mg 1 mg
EUR 718.8

Influenza A (NP) Antibody

abx023670-1mg 1 mg
EUR 718.8

Influenza A (NP) Antibody

abx023689-1mg 1 mg
EUR 718.8

Influenza A antibody (H1N1)

20C-CR1233GP 1 ml
EUR 511.2
Description: Goat polyclonal Influenza A antibody (H1N1)

Influenza A antibody (H3N2)

20C-CR1234GP 1 ml
EUR 501.6
Description: Goat polyclonal Influenza A antibody (H3N2)

Influenza A antibody (H1N1)

20-IG23 1 mg
EUR 139.2
Description: Goat polyclonal Influenza A antibody (H1N1)

Influenza A antibody (H3N2)

20-IG24 1 mg
EUR 139.2
Description: Goat polyclonal Influenza A antibody (H3N2)

Influenza A antibody (FITC)

61-I50A-F 100 ug
EUR 553.2
Description: Mouse monoclonal Influenza A antibody (FITC)

Influenza A antibody (FITC)

61C-CR1306M1F 100 ug
EUR 553.2
Description: Mouse monoclonal Influenza A antibody (FITC)

Influenza A antibody (Matrix)

20C-CR1235GP 1 ml
EUR 501.6
Description: Goat polyclonal Influenza A antibody (Matrix)

Influenza B Strain B/Tokyo/53/99 Antigen

11-578 0.1 mg
EUR 632.4
Description: Influenza B (B/Tokyo/53/99)

Influenza A Strain A/New Caledonia/20/99 IVR 116 (H1N1) Antigen Liquid

IFLUANCD2099IVR116H1N1ALR100UG each
EUR 738
Description: Influenza A Strain A/New Caledonia/20/99 IVR 116 (H1N1) Antigen Liquid

Influenza A HA H1 antibody

10-7839 500 ug
EUR 349.2
Description: Mouse monoclonal Influenza A haemagglutinin H1 antibody

Influenza A HA H1 antibody

10-7840 500 ug
EUR 349.2
Description: Mouse monoclonal Influenza A haemagglutinin H1 antibody

Influenza A HA H5 antibody

10-7854 1 mg
EUR 878.4
Description: Mouse monoclonal Influenza A HA H5 antibody

Influenza A HA H5 antibody

10-7855 1 mg
EUR 878.4
Description: Mouse monoclonal Influenza A HA H5 antibody

Influenza A HA H5 antibody

10-7856 1 mg
EUR 878.4
Description: Mouse monoclonal Influenza A HA H5 antibody

Influenza A H5 Antibody (HRP)

abx021962-1mg 1 mg
EUR 1888.8

Canine Influenza Virus (CIV) Antigen Test Card

C11331 15T Ask for price

Influenza A NS1 Antibody

abx021999-1mg 1 mg
EUR 961.2

Influenza A NP Antibody (FITC)

abx021956-100ug 100 ug
EUR 1011.6

Influenza B Strain B/Florida/04/06 Antigen

11-574 0.1 mg
EUR 632.4
Description: Influenza B (B/Florida/04/06), Influenza B Virus, Strain B/Florida/04/06

Influenza B Strain B/Florida/07/04 Antigen

11-575 0.1 mg
EUR 632.4
Description: Influenza B (B/Florida/07/04), Influenza B Virus, Strain B/Florida/07/04

Influenza B Strain B/Malaysia/2506/04 Antigen

11-577 0.1 mg
EUR 632.4
Description: Influenza B (B/Malaysia), Influenza B Virus, Strain B/Malaysia/2506/04

Influenza B Strain B/Victoria/504/00 Antigen

11-579 0.1 mg
EUR 632.4
Description: Influenza B (B/Victoria/504/00)

Avian Influenza A M2 Antibody

24577-100ul 100ul
EUR 468

Avian Influenza A M2 Antibody

4333-002mg 0.02 mg
EUR 206.18
Description: Avian Influenza A M2 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however, it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in Southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. The influenza membrane ion channel (M2) is a small transmembrane protein that regulates the pH inside the virion during viral entry into the cell and protects the newly synthesized hemagglutinin during their transport through low pH cellular compartments. It has been suggested as a target of neutralizing antibodies.

Avian Influenza A M2 Antibody

4333-01mg 0.1 mg
EUR 523.7
Description: Avian Influenza A M2 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however, it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in Southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. The influenza membrane ion channel (M2) is a small transmembrane protein that regulates the pH inside the virion during viral entry into the cell and protects the newly synthesized hemagglutinin during their transport through low pH cellular compartments. It has been suggested as a target of neutralizing antibodies.

Influenza A antibody (H1N1) (HRP)

60-I30 1 ml
EUR 556.8
Description: Goat polyclonal Influenza A antibody (H1N1) (HRP) conjugated

Influenza A antibody (H3N2) (HRP)

60-I39 1 ml
EUR 478.8
Description: Goat polyclonal Influenza A antibody (H3N2) (HRP) conjugated

Influenza A H1N1 antibody

10R-7791 50 ug
EUR 678
Description: Mouse monoclonal Influenza A H1N1 antibody

Influenza A H3N2 antibody

10R-7792 50 ug
EUR 678
Description: Mouse monoclonal Influenza A H3N2 antibody

Influenza A H5N1 antibody

10R-7793 50 ug
EUR 678
Description: Mouse monoclonal Influenza A H5N1 antibody

Influenza A H1N1 Antibody

abx023045-100ug 100 ug
EUR 1011.6

Influenza A H1N1 Antibody

abx023046-100ug 100 ug
EUR 961.2

Influenza A antibody (H1N1) (FITC)

60-I32 1 ml
EUR 440.4
Description: Goat polyclonal Influenza A antibody (H1N1) (FITC) conjugated

Influenza A antibody (H3N2) (FITC)

60-I33 1 ml
EUR 440.4
Description: Goat polyclonal Influenza A antibody (H3N2) (FITC) conjugated

Influenza A antibody (H1N1) (FITC)

60C-CR1233GF 1 ml
EUR 649.2
Description: Goat polyclonal Influenza A antibody (H1N1) (FITC) conjugated

Op glasplaatjes gedrukte eiwitarrays als platform om serodiagnostische antigenen  tegen bacteriële infecties te ontdekken

Infectieziekten vormen wereldwijd een belangrijke oorzaak van morbiditeit en mortaliteit. Vroege opsporing van infecties is van cruciaal belang voor het beheer van levensbedreigende gevallen . Tot nu toe zijn traditionele diagnostische methoden, zoals microbiologische culturen, traag en soms onnauwkeurig. In het moleculaire tijdperk zijn high-throughput-technieken essentieel voor het leveren van hulpmiddelen die in staat zijn om op een snelle en betrouwbare manier een diagnose te stellen, en ze kunnen ook worden gebruikt voor het bewaken van de humorale respons van groepen mensen in een programma van epidemiologische surveillance wanneer een uitbraak plaatsvindt, of wanneer een vaccin wordt geëvalueerd. Op antigeen gebaseerde eiwitmicroarrays zijn een ideaal middelvoor deze doeleinden, aangezien ze tot duizenden eiwitantigenen van pathogene bronnen kunnen dragen en kunnen worden onderzocht met sera van verschillende menselijke groepen (acute of chronisch geïnfecteerde mensen, herstellende, controles).

Voor de diagnose van bacteriële infecties zijn de beste antigenen in principe de oppervlakte-eiwitten, omdat deze de grootste kans hebben om een ​​effectieve immuunrespons op te wekken. Hier beschrijven we een algemeen protocol voor het fabriceren van een op glasplaatjes gebaseerde eiwitmicroarray met behulp van recombinante bacteriële oppervlakteantigenen, volgens onze eigen experience in de studie van pneumokokkenziekte. Het sonderen met menselijke sera heeft tot doel de verschillen tussen zieke en gezonde mensen te evalueren , om onderscheidende antigenen te ontdekken die, na gepaste validatie, kunnen worden gebruikt in andere gebruiksvriendelijke formaten zoals immunostrips.

Antigeen- presenterende, zelf-geassembleerde eiwit-nanovaten als een adjuvans-vrij vaccinplatform tegen het influenzavirus

Hoewel ze van nature voorkomen, zijn zelf-geassembleerde eiwit-nanoarchitecturen gebruikt als dragers voor het afleveren van antigeen, en het onvermogen van dergelijke dragers om immunogeniciteit op te wekken vereist aanvullend gebruik van sterke adjuvantia. Hier rapporteren we een immunogene  Brucella-  buitenmembraaneiwit BP26-afgeleide nanoarchitectuur die het extracellulaire influenzadomein van matrixproteïne-2 (M2e) als een vaccinplatform tegen influenzavirus weergeeft. Genetische manipulatie van een monomeer BP26 met vier of acht tandemherhalingen van M2e resulteerde in een holle tonvormige nanoarchitectuur (BP26-M2e nanobarrel). Immunisatie met BP26-M2e nanobarrels induceerde in vivo een sterke M2e-specifieke humorale immuunrespons  dat was veel groter dan dat van een fysisch mengsel van oplosbaar M2e en BP26, met of zonder het gebruik van een aluin-adjuvans.

Een anti- M2e- antilichaam gegenereerd door met BP26-M2e nanobarrel geïmmuniseerde muizen, specifiek gebonden aan met het influenzavirus geïnfecteerde cellen. Bovendien beschermden BP26-M2e-nanobarrels in virale challenge-tests muizen effectief tegen sterfte door influenzavirusinfectie, zelfs zonder het gebruik van een conventioneel adjuvans. Een mechanismestudie onthulde dat zowel M2e-specifieke antilichaamafhankelijke cellulaire cytotoxiciteit als T-celresponsen betrokken zijn bij de vaccineffectiviteit van BP26-M2e nanovaten. Deze bevindingen suggereren dat het op BP26 gebaseerde nanovat dat hier is ontwikkeld een veelzijdig vaccinplatform vertegenwoordigt dat kan worden gebruikt tegen verschillende virale infecties.

Prognostische impression van 18F-FDG PET/CT bij patiënten met agressief B-cellymfoom behandeld met anti-CD19 chimere  antigeenreceptor  T-cellen

Doel van het rapport:  We wilden de rol van 18F-FDG PET/CT evalueren bij het voorspellen van de uitkomst van de patiënt na infusie van chimere antigeenreceptor T (CAR T)-cellen bij agressief B-cellymfoom.

Methoden:  18F-FDG PET/CT-gegevens vóór leukaferese, vóór CAR T-celinfusie en 1 maand (M1) na CAR T-celinfusie, van 72 patiënten werden retrospectief geanalyseerd. SUVmax, totale laesie-glycolyse (TLG), metabool tumorvolume (MTV) en parameters die de tumorkinetiek beschrijven, werden berekend voor elke uitgevoerde 18F-FDG PET/CT. Het doel was om de prognostische waarde van 18F-FDG PET/CT metabole parameters te evalueren voor het voorspellen van progressievrije overleving (PFS) en algehele overleving (OS) na CAR T-celtherapie.

Resultaten: Met betrekking tot PFS bleken [INCREMENT]MTVpre-CAR en [INCREMENT]TLGpre-CAR meer discriminerend te zijn in vergelijking met metabole parameters bij pre-infusie. De mediane PFS bij patiënten met een [INCREMENT]MTVpre-CAR van minder dan 300% was 6,eight maanden (95% betrouwbaarheidsinterval [BI], 2,eight maanden tot niet bereikt) vergeleken met 2,eight maanden (95% BI, 0,9-3,Zero maanden) voor die met een waarde van 300% of meer (P = 0,004). Evenzo was de mediane PFS bij patiënten met [INCREMENT]TLGpre-CAR van minder dan 420% 6,eight maanden (95% BI, 2,eight maanden tot niet bereikt) vergeleken met 2,7 maanden (95% BI, 1,3-3,Zero maanden) voor degenen met een waarde van 420% of meer (P = 0,0148). Met betrekking tot OS waren metabole parameters op M1 sterk geassocieerd met de daaropvolgende uitkomst. SUVmax bij M1 met een afkapwaarde van 14 was de meest voorspellende parameter in multivariate analyse,

Conclusies: De  metabole volumekinetiek van de ziekte vóór infusie van CAR T-cellen lijkt superieur te zijn aan de initiële tumormassa zelf voor het voorspellen van PFS. Voor OS kan SUVmax bij M1 patiënten met verschillende prognoses adequaat scheiden.

CD9 Antigen (CD9) Antibody (PE)

abx134465-100Assays 100 Assays
EUR 594

CD9 Antigen (CD9) Antibody (PE)

abx134465-50Assays 50 Assays
EUR 477.6

CD9 Antigen (CD9) Antibody (PE)

abx200078-100tests 100 tests
EUR 543.6

CD9 Antigen (CD9) Antibody (PE)

abx139163-100tests 100 tests
EUR 577.2

CD9 Antigen (CD9) Antibody (PE)

abx140025-01mg 0.1 mg
EUR 444

CD44 Antigen (CD44) Antibody (PE)

abx134410-100Assays 100 Assays
EUR 594

CD44 Antigen (CD44) Antibody (PE)

abx134410-50Assays 50 Assays
EUR 477.6

CD63 Antigen (CD63) Antibody (PE)

abx134470-100Assays 100 Assays
EUR 594

CD63 Antigen (CD63) Antibody (PE)

abx134470-50Assays 50 Assays
EUR 477.6

CD44 Antigen (CD44) Antibody (PE)

abx200295-100tests 100 tests
EUR 661.2

CD63 Antigen (CD63) Antibody (PE)

abx200428-100tests 100 tests
EUR 543.6

CD44 Antigen (CD44) Antibody (PE)

20-abx200795
  • EUR 360.00
  • EUR 260.40
  • 100 ug
  • 25 ug

CD63 Antigen (CD63) Antibody (PE)

abx201086-100tests 100 tests
EUR 661.2

CD44 Antigen (CD44) Antibody (PE)

abx139278-100tests 100 tests
EUR 577.2

CD44 Antigen (CD44) Antibody (PE)

abx139282-100tests 100 tests
EUR 577.2

CD44 Antigen (CD44) Antibody (PE)

abx139286-01mg 0.1 mg
EUR 410.4

CD63 Antigen (CD63) Antibody (PE)

abx139314-100tests 100 tests
EUR 577.2

PE/Cyanine5 Anti-Mouse CD161/NK1.1 Antibody

DL20031F-20Tests 20Tests
EUR 152
Description: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

PE/Cyanine5 Anti-Mouse CD161/NK1.1 Antibody

DL20031F-50Tests 50Tests
EUR 212
Description: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

PE/Cyanine7 Anti-Mouse CD161/NK1.1 Antibody

DL20032F-20Tests 20Tests
EUR 152
Description: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

PE/Cyanine7 Anti-Mouse CD161/NK1.1 Antibody

DL20032F-50Tests 50Tests
EUR 212
Description: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

PE/Cyanine5.5 Anti-Mouse CD161/NK1.1 Antibody

DL20033F-20Tests 20Tests
EUR 152
Description: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

PE/Cyanine5.5 Anti-Mouse CD161/NK1.1 Antibody

DL20033F-50Tests 50Tests
EUR 212
Description: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

PE/Cyanine5 Anti-Mouse CD161/NK1.1 Antibody

DL20041F-25ug 25μg
EUR 230
Description: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

PE/Cyanine5 Anti-Mouse CD161/NK1.1 Antibody

DL20041F-50ug 50μg
EUR 335
Description: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

PE/Cyanine7 Anti-Mouse CD161/NK1.1 Antibody

DL20042F-25ug 25μg
EUR 222.5
Description: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

PE/Cyanine7 Anti-Mouse CD161/NK1.1 Antibody

DL20042F-50ug 50μg
EUR 320
Description: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

PE/Cyanine5.5 Anti-Mouse CD161/NK1.1 Antibody

DL20043F-25ug 25μg
EUR 230
Description: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

PE/Cyanine5.5 Anti-Mouse CD161/NK1.1 Antibody

DL20043F-50ug 50μg
EUR 357.5
Description: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

CD180 Antigen (CD180) Antibody (PE)

abx139718-100tests 100 tests
EUR 577.2

CD177 Antigen (CD177) Antibody (PE)

abx140142-100tests 100 tests
EUR 577.2

NK1.1 antibody (FITC)

61R-1154 100 ug
EUR 360
Description: Mouse monoclonal NK1.1 antibody (FITC)

NK1.1 antibody (biotin)

61R-1625 100 ug
EUR 340.8
Description: Mouse monoclonal NK1.1 antibody (biotin)

Nk1.1 Antibody / Cd161c

V8986-100UG 100ug
EUR 349.3
Description: NK-1.1 is commonly used as a mouse NK cell marker. It has also been shown to play a role in NK cell activation, IFN- production, and cytotoxic granule release. It is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by the Klrb1c/NKR-P1C gene. It is predominantly expressed as a disulfide-linked homodimer on NK cells however; it is also expressed on NK-T cells, a rare population of T lymphocytes. NK1.1 is expressed in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo.

Nk1.1 Antibody / Cd161c

V8986-20UG 20ug
EUR 153.3
Description: NK-1.1 is commonly used as a mouse NK cell marker. It has also been shown to play a role in NK cell activation, IFN- production, and cytotoxic granule release. It is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by the Klrb1c/NKR-P1C gene. It is predominantly expressed as a disulfide-linked homodimer on NK cells however; it is also expressed on NK-T cells, a rare population of T lymphocytes. NK1.1 is expressed in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo.

Nk1.1 Antibody / Cd161c

V8986SAF-100UG 100ug
EUR 349.3
Description: NK-1.1 is commonly used as a mouse NK cell marker. It has also been shown to play a role in NK cell activation, IFN- production, and cytotoxic granule release. It is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by the Klrb1c/NKR-P1C gene. It is predominantly expressed as a disulfide-linked homodimer on NK cells however; it is also expressed on NK-T cells, a rare population of T lymphocytes. NK1.1 is expressed in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo.

Carcinoembryonic Antigen (CEA) Antibody (PE)

20-abx270895
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Carcinoembryonic Antigen (CEA) Antibody (PE)

20-abx270927
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Carcinoembryonic Antigen (CEA) Antibody (PE)

20-abx270952
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

NK1.1 antibody (allophycocyanin)

61R-1784 100 ug
EUR 600
Description: Mouse monoclonal NK1.1 antibody (allophycocyanin)

Leukocyte Antigen CD37 (CD37) Antibody (PE)

abx134670-100Assays 100 Assays
EUR 594

Leukocyte Antigen CD37 (CD37) Antibody (PE)

abx134670-50Assays 50 Assays
EUR 477.6

Lymphocyte Antigen 75 (CD205) Antibody (PE)

abx139720-100tests 100 tests
EUR 577.2

Anti-F4/80 Antigen Antibody [BM8.1], PE-25ug

QAB68-PE-25ug 25ug
EUR 157.2

Anti-F4/80 Antigen Antibody [BM8.1], PE-100ug

QAB68-PE-100ug 100ug
EUR 301.2

T-Cell Antigen CD7 (CD7) Antibody (PE)

abx134629-100Assays 100 Assays
EUR 594

T-Cell Antigen CD7 (CD7) Antibody (PE)

abx134629-50Assays 50 Assays
EUR 477.6

T-Cell Antigen CD7 (CD7) Antibody (PE)

abx200058-100tests 100 tests
EUR 594

Anti-CD161c/NK1.1 Antibody

A30376 100ul
EUR 476.4
Description: Rabbit Polyclonal CD161c/NK1.1 Antibody. Validated in ELISA, WB and tested in Human, Mouse, Rat.

Leukocyte Antigen G (HLA-G) Antibody (PE)

abx139514-01mg 0.1 mg
EUR 828

Leukocyte Antigen G (HLA-G) Antibody (PE)

abx139517-01mg 0.1 mg
EUR 828

Leukocyte Antigen G (HLA-G) Antibody (PE)

abx139524-01mg 0.1 mg
EUR 828

Anti-Ms NK1.1 PE

1P-758-C025 0.025 mg
EUR 124.8

Anti-Ms NK1.1 PE

1P-758-C100 0.1 mg
EUR 200.4

Thy1 Cell Surface Antigen (Thy1) Antibody (PE)

20-abx270802
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

S Antigen (SAG) Polyclonal Antibody (Human), PE

4-PAB911Hu01-PE
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human S Antigen (SAG). This antibody is labeled with PE.

S Antigen (SAG) Polyclonal Antibody (Mouse), PE

4-PAB911Mu01-PE
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse S Antigen (SAG). This antibody is labeled with PE.

Anti-F4/80 Antigen Antibody [BM8.1], PE-Cy7-25ug

QAB68-PE7-25ug 25ug
EUR 218.4

B-Lymphocyte Antigen CD20 (CD20) Antibody (PE)

abx200174-100tests 100 tests
EUR 543.6

B-Lymphocyte Antigen CD20 (CD20) Antibody (PE)

abx139197-100tests 100 tests
EUR 577.2

B-Lymphocyte Antigen CD20 (CD20) Antibody (PE)

abx133981-100Assays 100 Assays
EUR 594

B-Lymphocyte Antigen CD20 (CD20) Antibody (PE)

abx133981-50Assays 50 Assays
EUR 477.6

Anti-F4/80 Antigen Antibody [BM8.1], PE-Cy7-100ug

QAB68-PE7-100ug 100ug
EUR 504

Neutrophil Specific Antigen 1 (NB1) Antibody (PE)

20-abx270838
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Rh Blood Group D Antigen (RhD) Antibody (PE)

abx201117-100tests 100 tests
EUR 577.2

Leukocyte Surface Antigen CD53 (CD53) Antibody (PE)

abx134484-100Assays 100 Assays
EUR 594

Leukocyte Surface Antigen CD53 (CD53) Antibody (PE)

abx134484-50Assays 50 Assays
EUR 477.6

Leukocyte Surface Antigen CD53 (CD53) Antibody (PE)

abx200367-100tests 100 tests
EUR 543.6

Leukocyte Surface Antigen CD53 (CD53) Antibody (PE)

abx139300-100tests 100 tests
EUR 577.2

T-Cell Surface Antigen CD2 (CD2) Antibody (PE)

abx200010-100tests 100 tests
EUR 543.6

T-Cell Surface Antigen CD2 (CD2) Antibody (PE)

abx139093-100tests 100 tests
EUR 577.2

T-Cell Surface Antigen CD2 (CD2) Antibody (PE)

abx139094-100tests 100 tests
EUR 577.2

T-Cell Surface Antigen CD2 (CD2) Antibody (PE)

abx139095-100tests 100 tests
EUR 577.2

Proliferating Cell Nuclear Antigen (PCNA) Antibody (PE)

abx140395-100tests 100 tests
EUR 577.2

Carbohydrate Antigen 125 (CA125) Polyclonal Antibody (Human), PE

4-PAA154Hu01-PE
  • EUR 334.80
  • EUR 2874.00
  • EUR 825.60
  • EUR 416.40
  • EUR 225.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Carbohydrate Antigen 125 (CA125). This antibody is labeled with PE.

Carbohydrate Antigen 125 (CA125) Polyclonal Antibody (Mouse), PE

4-PAA154Mu01-PE
  • EUR 339.60
  • EUR 2942.40
  • EUR 843.60
  • EUR 423.60
  • EUR 226.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Carbohydrate Antigen 125 (CA125). This antibody is labeled with PE.

Monocyte Differentiation Antigen CD14 (CD14) Antibody (PE)

abx134477-100Assays 100 Assays
EUR 594

Monocyte Differentiation Antigen CD14 (CD14) Antibody (PE)

abx134477-50Assays 50 Assays
EUR 477.6

Monocyte Differentiation Antigen CD14 (CD14) Antibody (PE)

abx200128-100tests 100 tests
EUR 543.6

Monocyte Differentiation Antigen CD14 (CD14) Antibody (PE)

abx139171-100tests 100 tests
EUR 577.2

Monocyte Differentiation Antigen CD14 (CD14) Antibody (PE)

abx139177-100tests 100 tests
EUR 577.2

Carcinoembryonic Antigen (CEA) Polyclonal Antibody (Rat), PE

4-PAA150Hu01-PE
  • EUR 270.00
  • EUR 1958.40
  • EUR 597.60
  • EUR 325.20
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Carcinoembryonic Antigen (CEA). This antibody is labeled with PE.

Tn antigen antibody

10R-6775 1 ml
EUR 482.4
Description: Mouse monoclonal Tn antigen antibody

La Antigen Antibody

E90630 100μg
EUR 255
Description: Available in various conjugation types.

T-cell Activation Antigen CD27 (CD27) Antibody (PE)

abx200209-100tests 100 tests
EUR 594

T-cell Activation Antigen CD27 (CD27) Antibody (PE)

abx139211-100tests 100 tests
EUR 577.2

Purified anti-mouse NK1.1 Antibody

E16FMUNK1.1-050U 50 μg
EUR 100
Description: Available in various conjugation types.

Purified anti-mouse NK1.1 Antibody

E16FMUNK1.1-100U 100 μg
EUR 160
Description: Available in various conjugation types.

Purified anti-mouse NK1.1 Antibody

E16FMUNK1.1-500U 500 μg
EUR 513.33
Description: Available in various conjugation types.

RNP Antigen Antibody

abx022696-2ml 2 ml
EUR 693.6

Myeloid Cell Surface Antigen CD33 (CD33) Antibody (PE)

abx134572-100Assays 100 Assays
EUR 594

Myeloid Cell Surface Antigen CD33 (CD33) Antibody (PE)

abx134572-50Assays 50 Assays
EUR 477.6

Myeloid Cell Surface Antigen CD33 (CD33) Antibody (PE)

abx134573-100Assays 100 Assays
EUR 594

Myeloid Cell Surface Antigen CD33 (CD33) Antibody (PE)

abx134573-50Assays 50 Assays
EUR 477.6

Myeloid Cell Surface Antigen CD33 (CD33) Antibody (PE)

abx200231-100tests 100 tests
EUR 543.6

Myeloid Cell Surface Antigen CD33 (CD33) Antibody (PE)

abx139243-100tests 100 tests
EUR 577.2

B-Lymphocyte Antigen CD20 (CD20) Antibody (PE-Cy5)

abx133982-100Assays 100 Assays
EUR 594

B-Lymphocyte Antigen CD20 (CD20) Antibody (PE-Cy5)

abx133982-50Assays 50 Assays
EUR 477.6

Carcinoembryonic Antigen (CEA) Polyclonal Antibody (Human), PE

4-PAA150Hu02-PE
  • EUR 270.00
  • EUR 1958.40
  • EUR 597.60
  • EUR 325.20
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Carcinoembryonic Antigen (CEA). This antibody is labeled with PE.

Carcinoembryonic Antigen (CEA) Polyclonal Antibody (Human), PE

4-PAA150Hu03-PE
  • EUR 270.00
  • EUR 1958.40
  • EUR 597.60
  • EUR 325.20
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Carcinoembryonic Antigen (CEA). This antibody is labeled with PE.

Carcinoembryonic Antigen (CEA) Polyclonal Antibody (Mouse), PE

4-PAA150Mu01-PE
  • EUR 295.20
  • EUR 2320.80
  • EUR 687.60
  • EUR 361.20
  • EUR 208.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Carcinoembryonic Antigen (CEA). This antibody is labeled with PE.

Renal Tumor Antigen (RAGE) Polyclonal Antibody (Rat), PE

4-PAH266Ra01-PE
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Renal Tumor Antigen (RAGE). This antibody is labeled with PE.

T-Cell Differentiation Antigen CD6 (CD6) Antibody (PE)

abx200051-100tests 100 tests
EUR 543.6

T-Cell Differentiation Antigen CD6 (CD6) Antibody (PE)

abx139146-100tests 100 tests
EUR 577.2

Nuclear Antigen Antibody

V3107-100UG 100 ug
EUR 349.3
Description: This mAb is an excellent marker for all nuclei in cells in tissues. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This mAb recognizes an antigen associated with the nuclei in all cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions. It produces a speckled pattern in normal and malignant cells and may be used to stain the nuclei of cells in fixed tissue sections.

Nuclear Antigen Antibody

V3107-20UG 20 ug
EUR 153.3
Description: This mAb is an excellent marker for all nuclei in cells in tissues. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This mAb recognizes an antigen associated with the nuclei in all cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions. It produces a speckled pattern in normal and malignant cells and may be used to stain the nuclei of cells in fixed tissue sections.

Nuclear Antigen Antibody

V3107IHC-7ML 7 ml
EUR 349.3
Description: This mAb is an excellent marker for all nuclei in cells in tissues. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This mAb recognizes an antigen associated with the nuclei in all cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions. It produces a speckled pattern in normal and malignant cells and may be used to stain the nuclei of cells in fixed tissue sections.

Nuclear Antigen Antibody

V3107SAF-100UG 100 ug
EUR 349.3
Description: This mAb is an excellent marker for all nuclei in cells in tissues. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This mAb recognizes an antigen associated with the nuclei in all cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions. It produces a speckled pattern in normal and malignant cells and may be used to stain the nuclei of cells in fixed tissue sections.

Nuclear Antigen Antibody

V8854-100UG 100ug
EUR 349.3
Description: This MAb is an excellent marker for all nuclei in cells in tissues. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes an antigen associated with the nuclei in all cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions.

Nuclear Antigen Antibody

V8854-20UG 20ug
EUR 153.3
Description: This MAb is an excellent marker for all nuclei in cells in tissues. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes an antigen associated with the nuclei in all cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions.

Nuclear Antigen Antibody

V8854SAF-100UG 100ug
EUR 349.3
Description: This MAb is an excellent marker for all nuclei in cells in tissues. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes an antigen associated with the nuclei in all cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions.

Nuclear Antigen Antibody

V7192-100UG 100 ug
EUR 349.3
Description: This mAb recognizes an antigen associated with the nuclei in cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions.

Nuclear Antigen Antibody

V7192-20UG 20 ug
EUR 153.3
Description: This mAb recognizes an antigen associated with the nuclei in cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions.

Nuclear Antigen Antibody

V7192IHC-7ML 7 ml
EUR 349.3
Description: This mAb recognizes an antigen associated with the nuclei in cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions.

Nuclear Antigen Antibody

V7192SAF-100UG 100 ug
EUR 349.3
Description: This mAb recognizes an antigen associated with the nuclei in cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions.

Nuclear Antigen Antibody

V7504-100UG 100 ug
EUR 349.3
Description: This MAb is an excellent marker for all nuclei in cells in tissues. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes an antigen associated with the nuclei in all cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions. It produces a speckled pattern in normal and malignant cells.

Nuclear Antigen Antibody

V7504-20UG 20 ug
EUR 153.3
Description: This MAb is an excellent marker for all nuclei in cells in tissues. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes an antigen associated with the nuclei in all cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions. It produces a speckled pattern in normal and malignant cells.

Nuclear Antigen Antibody

V7504IHC-7ML 7 ml
EUR 349.3
Description: This MAb is an excellent marker for all nuclei in cells in tissues. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes an antigen associated with the nuclei in all cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions. It produces a speckled pattern in normal and malignant cells.

Nuclear Antigen Antibody

V7504SAF-100UG 100 ug
EUR 349.3
Description: This MAb is an excellent marker for all nuclei in cells in tissues. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes an antigen associated with the nuclei in all cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in subcellular fractions. It produces a speckled pattern in normal and malignant cells.

Lymphocyte Antigen 9 (LY9) Polyclonal Antibody (Human), PE

4-PAB678Hu01-PE
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Lymphocyte Antigen 9 (LY9). This antibody is labeled with PE.

Lymphocyte Antigen 9 (LY9) Polyclonal Antibody (Mouse), PE

4-PAB678Mu01-PE
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Lymphocyte Antigen 9 (LY9). This antibody is labeled with PE.

Sp100 Nuclear Antigen (Sp100) Polyclonal Antibody (Rat), PE

4-PAA326Ra01-PE
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Sp100 Nuclear Antigen (Sp100). This antibody is labeled with PE.

Forssman antigen antibody

10R-8066 100 ug
EUR 586.8
Description: Rat monoclonal Forssman antigen antibody

Forssman antigen antibody

10R-8067 100 ug
EUR 586.8
Description: Rat monoclonal Forssman antigen antibody

Lymphocyte Antigen 96 (LY96) Polyclonal Antibody (Human), PE

4-PAH705Hu01-PE
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Lymphocyte Antigen 96 (LY96). This antibody is labeled with PE.

Lymphocyte Antigen 96 (LY96) Polyclonal Antibody (Mouse), PE

4-PAH705Mu01-PE
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Lymphocyte Antigen 96 (LY96). This antibody is labeled with PE.

Lymphocyte Antigen 75 (LY75) Polyclonal Antibody (Mouse), PE

4-PAB593Mu01-PE
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Lymphocyte Antigen 75 (LY75). This antibody is labeled with PE.

Cellular Tumor Antigen P53 (p53) Antibody (PE/ATTO 594)

abx446378-100ug 100 ug
EUR 710.4

Cellular Tumor Antigen P53 (p53) Antibody (PE/ATTO 594)

abx443713-100ug 100 ug
EUR 627.6

Sp100 Nuclear Antigen (Sp100) Polyclonal Antibody (Human), PE

4-PAA326Hu01-PE
  • EUR 333.60
  • EUR 2856.00
  • EUR 822.00
  • EUR 415.20
  • EUR 224.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Sp100 Nuclear Antigen (Sp100). This antibody is labeled with PE.

Sp100 Nuclear Antigen (Sp100) Polyclonal Antibody (Mouse), PE

4-PAA326Mu01-PE
  • EUR 339.60
  • EUR 2942.40
  • EUR 843.60
  • EUR 423.60
  • EUR 226.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Sp100 Nuclear Antigen (Sp100). This antibody is labeled with PE.

Bone Marrow Stromal Cell Antigen 1 (BST1) Antibody (PE)

20-abx270830
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

FOS Like Antigen 1 (FOSL1) Polyclonal Antibody (Rat), PE

4-PAJ089Ra01-PE
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat FOS Like Antigen 1 (FOSL1). This antibody is labeled with PE.

Lymphocyte Function Associated Antigen 2 (LFA2) Antibody (PE)

20-abx270774
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Lymphocyte Function Associated Antigen 2 (LFA2) Antibody (PE)

20-abx270785
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Lymphocyte Function Associated Antigen 3 (LFA3) Antibody (PE)

20-abx270818
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

G antigen 5 Antibody

20-abx109796
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (PE)

abx134247-100Assays 100 Assays
EUR 594

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (PE)

abx134247-50Assays 50 Assays
EUR 477.6

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (PE)

abx200237-100tests 100 tests
EUR 627.6

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (PE)

20-abx200773
  • EUR 710.40
  • EUR 376.80
  • 100 ug
  • 25 ug

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (PE)

abx139247-100tests 100 tests
EUR 577.2

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (PE)

abx139249-100tests 100 tests
EUR 577.2

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody (PE)

abx140196-100tests 100 tests
EUR 577.2

Paraneoplastic Antigen MA2 (PNMA2) Polyclonal Antibody (Rat), PE

4-PAH343Ra01-PE
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Paraneoplastic Antigen MA2 (PNMA2). This antibody is labeled with PE.

Jo-1 Antigen Antibody

abx022693-2ml 2 ml
EUR 961.2

SS-B Antigen Antibody

abx022700-2ml 2 ml
EUR 543.6

CD62 Antigen-Like Family Member P (CD62P) Antibody (PE)

abx134168-100Assays 100 Assays
EUR 594

CD62 Antigen-Like Family Member P (CD62P) Antibody (PE)

abx134168-50Assays 50 Assays
EUR 477.6

CD62 Antigen-Like Family Member L (CD62L) Antibody (PE)

abx134418-100Assays 100 Assays
EUR 594

CD62 Antigen-Like Family Member L (CD62L) Antibody (PE)

abx134418-50Assays 50 Assays
EUR 477.6

CD62 Antigen-Like Family Member P (CD62P) Antibody (PE)

abx200406-100tests 100 tests
EUR 543.6

CD62 Antigen-Like Family Member P (CD62P) Antibody (PE)

abx200412-100tests 100 tests
EUR 543.6

CD62 Antigen-Like Family Member E (CD62E) Antibody (PE)

abx200417-100tests 100 tests
EUR 777.6

CD62 Antigen-Like Family Member L (CD62L) Antibody (PE)

abx200422-100tests 100 tests
EUR 543.6

CD62 Antigen-Like Family Member L (CD62L) Antibody (PE)

20-abx200868
  • EUR 444.00
  • EUR 326.40
  • 100 ug
  • 25 ug

CD62 Antigen-Like Family Member L (CD62L) Antibody (PE)

abx139858-100tests 100 tests
EUR 577.2

CD62 Antigen-Like Family Member P (CD62P) Antibody (PE)

abx139866-100tests 100 tests
EUR 577.2

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